Publications by authors named "I I Sheleketina"

Common aspects have been revealed of structural and functional disorders of the biliary tract and intestine in elderly patients with digestive pathology. We recommend that lipotropic drugs, choleretics, cholekinetics, antioxidants and eubiotics be used in the treatment of the above patients.

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Using cluster analysis of analytic strips optical densities the lithogenic bile heterogeneity has been confirmed and different types, possessing a distinction totality of spectral and biochemical figures has been revealed. This study demonstrated tendency in process of formation of gallstone in cholelithiasis.

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Our studies on phosphatide, a food concentrate, produced as a by-product during the extraction of an edible oil in the oil-extraction plants, showed its high efficacy in patients (n = 52) with abnormalities of the hepatobiliary system. The drug having more than 40 weight percent of phosphorus-containing lipids appeared to be efficacious not only in respect of the subjective status of the patients but also the functional state of the liver and paraments characterizing lipid metabolism.

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The ionization and conjugation effect on infrared spectra of bile acids has been studied. The interpretation of spectra of native bile absorption in the infrared range was conducted with allowance for different types of functional groups oscillations.

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Acute, subacute, and chronic experiments were performed to examine the toxicity, specific action, analgetic, and physicochemical properties of suicrepan derived from the porcine duodenal mucosa and the hormone secretin contained in it. Suicrepan was found to be an effective pancreatic extrasecretory function stimulant, by showing therapeutical benefits in experimental pancreatitis and analgesic effects. The drug was demonstrated to display a low toxicity.

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