Publications by authors named "I I Shaposhnik"
Aim To evaluate the role of iron deficiency (ID) identified by various criteria, anemia, and the combination of ID and anemia in determining the severity of the clinical course of chronic heart failure (CHF) in a retrospective analysis of data from 498 patients who participated in the ID-CHF-RF Russian multicenter program.Material and methods ID was diagnosed by the following three criteria established by the European Society of Cardiology (ESC) and the Russian Society of Cardiology (RSC): 1) ferritin concentration <100 μg/l or ferritin concentration 100-299 μg/l in combination with a decreased transferrin saturation (TS) <20%; 2) ID criteria that showed a high sensitivity and specificity when compared with bone marrow morphology (BMM): TS ≤19.8% or serum iron (SI) ≤13 μmol/l; and 3) a composite index including a ferritin concentration <100 μg/l in combination with TS <20% and SI ≤13 μmol/l.
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- The study compares clinical and lab data of chronic heart failure (CHF) patients with iron deficiency (ID) based on two different diagnostic criteria: AHA/ESC/RSC guidelines and a stricter definition involving low transferrin saturation (TSAT) and serum iron levels.
- Among 498 patients analyzed, ID was identified in 83.1% using AHA/ESC/RSC criteria and 74.5% using the TSAT/serum iron criteria, with many patients meeting both sets of criteria.
- Those diagnosed with ID based on the TSAT/serum iron criteria experienced more severe CHF symptoms, higher rates of anemia and diabetes, and showed significant differences in lab results and age compared to those diagnosed solely
Article Synopsis
- The study aimed to analyze clinical data from patients with non-obstructive ischemic heart disease (IHD) and multifocal atherosclerosis (MFA) in the KAMMA registry, focusing on those who underwent coronary angiography (CAG).
- Out of 1,893 IHD patients, only 8.7% had non-obstructive coronary atherosclerosis (CA), with many affected by MFA in various arteries, especially the brachiocephalic and lower extremity arteries.
- Patients with non-obstructive CA, predominantly women, had fewer traditional risk factors like smoking and diabetes, but higher cholesterol levels; they also experienced less severe IHD and acute coronary syndrome compared to those with obstructive
Aim To study prognostic significance of the degree of stenosis of carotid and lower-extremity arteries (LEA) in patients at high and very high risk of cardiovascular complications (CVC).Material and methods The study included men and women aged 40-67 years at high and very high risk of CVC. Duplex ultrasound scanning of carotid arteries and LEA was performed for all patients.
View Article and Find Full Text PDFAim To evaluate the incidence of iron deficiency (ID) in men and women with chronic heart failure (CHF) and to compare clinical and functional indexes in patient with and without ID depending on the gender.Material and methods An additional analysis of the study "Prevalence of Iron Deficiency in Patients With Chronic Heart Failure in the Russian Federation (ID-CHF-RF)" was performed. The study included 498 (198 women, 300 men) patients with CHF, in whom, in addition to iron metabolism, the quality of life and exercise tolerance (ET) were studied.
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