Publications by authors named "I I Sapozhnikov"

The objective of the present study was to evaluate the functional state of the auditory analyzer in infants born prematurely (after 29 weeks of gestation) and examined at 6 months of life. The evoked otoacoustic emission (EOAE) techniques were used for the purpose. Testing with the help of two different modes of EOAE yielded virtually identical results which confirms the possibility to apply both delayed EOAE (dEOAE) and distortion-product frequency OAE (dpOAE) for the assessment of the auditory function.

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The objective of the present study was to assess the state of the peripheral portion of the auditory analyzer based on induced otoacoustic emissions (IOAEs), distortion product otoacoustic emissions (DPOAEs), and delayed IOAEs (DIOAEs). The study included 31 premature infants born before 28 weeks gestation and examined later on the 6th month of postnatal life. All of them were shown to have the underdeveloped cochlea.

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Experiments on guinea pigs with the use of electrophysiological methods (short-latency auditory evoked potentials, SLAEPs, and distortion product otoacoustic emission, DPOAE) have demonstrated damage of outer hair cells following application of therapeutic doses of cisplatin. It is concluded that finding of the logarithmic amplitude-time dependence for the first SLAEPs peak permits to diagnose an injury to outer hair cells.

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Premature infants are highly vulnerable to developing various pathologies including eye and ear diseases; some of them are believed to be associated with specific individual features of gestation and labour course. The study included audiologic screening of 148 babies (296 ears) born prematurely during 24-37 weeks of pregnancy (delayed evoked otoacoustic emission was recorded at the distortion product frequency). For the purpose of dynamic evaluation of hearing ability, all the infants were divided into 3 groups depending on gestational age at birth; they were followed up throughout the first year of life.

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Audiological screening by registration of delayed evoked distortion product otoacoustic emission (DPOE) was made in 148 premature neonates (296 ears) born at gestation week 24-37. All the examinees were divided into three groups depending on the gestation term and were followed up for the first year of life. The results of the screening tests with reference to postconceptional and real age of premature infants are given.

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