[Neonatal buspirone modulates the intermale aggression in adult mice].

Mice of two strains with different levels of male aggression (RSB and RLB) were subjected to daily injections of 5-HT1A receptor agonist buspirone (25 microg) on the 2nd - 6th postnatal days. This neonatal treatment augmented the aggressive behavior (tested in the dyadic contests with non-aggressive A/Sn males) in aggressive RSB mice and reduced aggression in less aggressive RLB. Correlations with different signs were found between the 5-HT and 5-HIAA levels in the neocortex, hippocampus, and hypothalamus and behavioral indices of aggression in RSB and RLB males.

[Variants of left ventricular hypertrophy in patients on programmed hemodialysis].

Programmed hemodialysis (PHD) was successfully used in 189 of 207 patients with chronic renal failure (CRF) treated in Ulyanovsk Regional Hemodialysis Center for 10 years. To improve PHD results and prevent fatal complications, a search for objective prognostic indices of cardiovascular disease function was initiated. Left ventricular hypertrophy (LVH) development was compared in two groups of patients of different age (group 1--69 young patients aged 18-40 years; group 2--48 elderly patients aged 55-73 years.