[The modification of a radiation lesion with 9a-homo-13-thiaprostanoids].

The radioprotective properties of 12 compounds of 9a-homo-13-thiaprostanoid series were investigated under gamma irradiation using the molecular model of beta-carotene radio-oxidation in oleic acid in vitro, erythrocyte radiomimetic model in ex vivo-in vitro system as well as in vivo radiation damage in mice. Most of these compounds stimulated the radio-oxidation of beta-carotene, however in this model two prostanoids with natural alpha-chain displayed radioprotective properties. Expressed membrane stabilizing effect of two 9a-homo-13-thiaprostanoid nor-analogues was revealed in radiomimetic model experiments.

[Proton magnetic resonance spectra of bound water in muscles].

The state of water in a muscle tissue was investigated using 1H-NMR. Water spectra in the muscle were found after holding it out at variable humidity and after the muscle species had been pressed with different effort. The NMR-spectra demonstrated the existence of two different water fractions with poor exchange between them.

[ATP synthesis by myosin during pH-jump].

It has been shown that a fast increase in pH of myosin solution leads to ATP formation de novo from ADP and Pi (about one ATP molecule per one myosin molecule). The obligatory condition for ATP synthesis was that the value of pH 7.9-8.