Publications by authors named "I I Ogbu"
Article Synopsis
- A narrative review analyzed peer-reviewed studies to explore how sleep-disordered breathing (SDB) links to cardiac arrhythmias through factors like intermittent hypoxia and autonomic imbalance.
- Patients with SDB face significantly higher risks for various heart rhythm issues, with more than double the chance of overall arrhythmias and a quadrupled risk of atrial fibrillation (AF).
- CPAP therapy is shown to be an effective treatment, reducing AF recurrence and lowering the risk of ventricular arrhythmias, emphasizing the need for early diagnosis and management of SDB to improve heart health.
Article Synopsis
- Cardiac amyloidosis (CA) is a challenging heart condition characterized by the buildup of amyloid proteins, leading to poor outcomes but improvements in diagnosis and treatment options are underway.
- The article discusses treatment advancements for two main types: transthyretin cardiac amyloidosis (ATTR-CA) and light chain mediated cardiac amyloidosis (AL-CA), highlighting promising therapies for ATTR-CA that target amyloid fibril formation.
- Current treatment for AL-CA typically involves chemotherapy, and successful management of CA relies on a team of specialists from various medical fields to address patient needs effectively.
Article Synopsis
- * OSA negatively impacts brain structure and cognitive function, making it crucial to understand its role in the heart-brain connection, particularly regarding cerebral small vessel disease and neurocognitive decline.
- * The review seeks to summarize the connections between OSA and neurocognitive disorders, explore the cardio-neural mechanisms involved, and discuss potential treatment options for affected patients.
Sodium-glucose co-transporter 2 (SGLT2) inhibitors have demonstrated efficacy in slowing the progression of chronic kidney disease (CKD), managing conditions such as congestive heart failure (CHF), and reducing cardiovascular and overall mortality in patients with type 2 diabetes mellitus (T2DM). However, their use is associated with complications, including euglycemic diabetic ketoacidosis (euDKA), genital fungal infections, and urinary tract infections (UTIs). Although rare, complications like euDKA can lead to serious consequences if not promptly addressed, as illustrated by this case report of a 90-year-old man with ischemic cardiomyopathy and type 2 diabetes who developed both euDKA and a UTI while on SGLT2 inhibitor therapy.
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