Selective and self-guided micro-ablation of tissue with plasmonic nanobubbles.

Background: The accuracy, selectivity, and safety of surgical and laser methods for tissue elimination are often limited at microscale.

Materials And Methods: We developed a novel agent, the plasmonic nanobubble (PNB), for optically guided selective elimination of the target tissue with micrometer precision. PNBs were tested in vitro in the two different models of superficial tumors and vascular plaques.

[Hygienic evaluation of hydrolytic lignin waste, by using alternative test models].

Chemical analysis showed that lignin samples contained phenols, phenanthrene, and methanol. The highest total content of organic compounds was noted in the lignin samples taken directly at a manufacturing plant. Phenols prevailed in the upper layers of stored lignin samples and methanol predominated in the lower ones.

Hunting the mechanisms of self-renewal of immortal cell populations by means of real-time imaging of living cells.

The causes of the indefinite propagation of immortalized cell populations remain insufficiently understood, that hinders the research of such fundamental processes as ageing and cancer. In this study the interrelations between clonal proliferation and abnormalities of mitotic divisions in the immortalized cell line established from the mouse embryo were investigated with the aid of computerized microscopy of living cells. 3 mitoses with three daughter cells and 7 asymmetric mitoses which generated two daughter cells of conspicuously different sizes were registered among 71 mitotic divisions in the individual cell genealogy.