[Prolonged paravertebral analgesia in therapy of chronic pain syndrome in critical lower-limb ischaemia].

Chronic pain syndrome in patients presenting with lower-limb critical ischaemia may have considerable significance in progression of the degree of limb ischaemia, and quality of life of patients appears to be largely determined by adequate analgesia. Currently, there is no 'gold standard' of therapy for chronic pain syndrome in critical lower-limb ischaemia, which makes it necessary to search for new effective and safe methods of analgesia. The purpose of this study was to evaluate efficacy and safety of paravertebral analgesia compared with epidural analgesia in therapy of chronic pain syndrome in critical lower-limb ischaemia.

[Sulodexide in treatment of chronic venous insufficiency. Results of the All-Russian multicenter programme ACVEDUCT].

Introduction: Pharmacotherapy occupies one of the leading places in comprehensive treatment of lower-limb chronic venous diseases (CVD) and their complications. At the same time, there are not so many therapeutic agents intended for treatment of CVD and possessing evidence-based efficacy. Sulodexide (registered in Russia as Vessel Due F) is a drug with a confirmed therapeutic effect in patients with a moderately severe course of chronic venous disease or its late stages.

[Results of splenorenal venous bypass grafting in patients with hepatocirrhosis].

Presented herein are the results of surgical treatment of 79 patients with intrahepatic portal hypertension who underwent splenorenal venous bypass grafting after splenectomy. The patients' age varied from 8 to 64 years, averaging 37.3 years.

[Possibility of operative treatment of geriatric patients with critical lower limb ischemia].

The experience of treating 106 patients of 70+ years shows the possibility of successful vascular reconstructive procedures with good immediate and long-term results, even in the presence of critical limb ischemia and severe comorbidity in geriatric patients, if not guided by the principle of maximum revascularization of the affected limbs, and minimally sufficient, through a wide use of atypical and small renovations. In addition, not only comprehensive assessment of the reserve and compensatory capacities of the patients is important, but also preoperative prevention of cardiac, pulmonary and other complications.

[Substantiation of an adequate scope of diagnostic methods and surgical procedures in patients with diabetic foot syndrome].

Analysed herein are the results of treating a total of 154 patients presenting with diabetes mellitus and pyo-necrotic alterations in the lower limbs. Duration of diabetes prior to the development of necrotic complications averagely amounted to 15 years, in 76 patients of the Study Group we determined the species-specific composition of the pathogens, the number of microbial bodies in 1 gram of necrotic tissues as well as the state of cellular and humoral immunity, and the complex of therapeutic measures was supplemented by cytokine therapy: Operative treatment in 78 patients of the control group consisted of various-scope necrectomies and open management of the wounds. The operative procedures in the Study Group patients included revascularizing operations, as well as secondary surgical debridement of the wounds with placing sutures.