Publications by authors named "I I Kagan"

Background: Preserving new graduate nurses in the profession is an essential step for addressing the nursing shortage and sustaining the future of the profession. This study aimed to examine the relationship between employment characteristics and job satisfaction of novice nurses and their willingness to stay in the nursing profession in the next 5 years.

Methods: Novice nurses' intention to stay in the profession was assessed, considering demographics, employment characteristics, and components of job satisfaction.

View Article and Find Full Text PDF

A positive-sense single-stranded RNA virus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), caused the coronavirus disease 2019 (COVID-19) pandemic that devastated the world. While this is a respiratory virus, one feature of the SARS-CoV-2 infection was recognized to cause pathogenesis of other organs. Because the membrane fusion protein of SARS-CoV-2, the spike protein, binds to its major host cell receptor angiotensin-converting enzyme 2 (ACE2) that regulates a critical mediator of cardiovascular diseases, angiotensin II, COVID-19 is largely associated with vascular pathologies.

View Article and Find Full Text PDF
Article Synopsis
  • Acinetobacter baumanni infections are common and serious in ICUs, making early detection crucial for better patient outcomes.
  • This study developed a Machine Learning prediction tool using data from nearly 20,000 ICU patients to identify those at risk for these infections.
  • The tool showed moderate predictive ability, with key risk factors being respiratory function, metabolic issues, and antibiotic use, suggesting areas for improving prediction accuracy in the future.*
View Article and Find Full Text PDF
Article Synopsis
  • Glycemic control during critical illness is crucial, with recommendations suggesting insulin therapy for glucose levels over 180 mg/dL, and possibly lowering it to 140 mg/dL for non-diabetics; this study explored the relationship between different glucose thresholds and 90-day mortality.
  • A retrospective study analyzed data from 1,429 critical patients, revealing that diabetic individuals had higher mean glucose levels and mortality rates compared to non-diabetics.
  • The findings indicated that non-diabetic patients with glucose levels exceeding 150 mg/dL were at a greater risk of mortality within 90 days, highlighting the importance of managing hyperglycemia in this group.
View Article and Find Full Text PDF

Neuroeconomics theories propose that the value associated with diverse rewards or reward-predicting stimuli is encoded along a common reference scale, irrespective of their sensory properties. However, in a dynamic environment with changing stimulus-reward pairings, the brain must also represent the sensory features of rewarding stimuli. The mechanism by which the brain balances these needs-deriving a common reference scale for valuation while maintaining sensitivity to sensory contexts-remains unclear.

View Article and Find Full Text PDF