Publications by authors named "I I K Umeda"

A 59-year-old man presented with abdominal mass and weight loss. Computed tomography revealed a 20 cm mass in the vicinity of the left kidney. A tumor biopsy was performed and diagnosed with leiomyosarcoma.

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Article Synopsis
  • Researchers explored using fungal fermentation, specifically Aspergillus niger, to treat hydrothermal liquefaction aqueous phase (HTLAP) from corn stover, showing its ability to tolerate HTLAP and produce oxalic acid.
  • A co-culture of A. niger and Rhodococcus jostii effectively removed 69% of chemical oxygen demand (COD) at a lower loading, while also generating oxalic acid and microbial biomass with lipid content.
  • At higher COD levels, while R. jostii struggled, A. niger thrived and increased oxalic acid production without significantly affecting COD removal, demonstrating the potential for converting HTLAP into valuable products.
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Intrahepatic splenosis (IHS) is a rare disease that is considered to result from heterotopic autotransplantation or implantation of splenic tissue after splenic trauma or surgery. A 46-year-old man with a treatment history of a left lateral liver segmentectomy and splenectomy for a road traffic injury 30 years earlier presented to Sakai City Medical Center (Sakai, Japan) with acute abdominal pain in November 2019. Physical examination showed no significant signs, and serum data were normal.

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Radionuclide imaging and therapy are promising methods for controlling systemic cancers; however, their clinical application has been limited by excessive radionuclide accumulation in healthy tissues. To minimize radionuclide accumulation in non-cancerous tissues while ensuring sufficient build up in tumors, we aimed to develop a method that controlled the in vivo dynamics of radionuclides post-administration. To this end, we describe a novel strategy that combines liposomes, a potent carrier system for drug delivery, with unique radionuclide-ligand complexes based on In-ethylenedicysteine.

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Although the advent of molecular-targeted drugs has improved the prognosis of various cancers, the long-term prognosis and side effects as the first-line therapy for metastatic choroidal tumors remain unclear. We describe a case in which the first-line therapy of osimertinib has shown long-term successful and minimum side effect responses for metastatic choroidal tumors in a patient with advanced-stage lung cancer. The patient was a 62-year-old man who complained of foggy vision and visual field defects in his left eye for 1 month.

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