Publications by authors named "I I Grin'ko"

Use of enterosorption during the first week of extrahepatic cholestasis in rats led to decrease of disorders in functional state of liver tissue and its subcellular organelles as well as of accumulation of toxic substances in organism. The main effect of enterosorption appears to be binding of Gram-negative bacteria endotoxin in intestine.

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It was established in experiments on dogs that the effect of hemosorption on the mitochondrial apparatus and the lysosomal system of the hepatic cells in extrahepatic cholestasis depends on the stage of the pathological process and the corresponding prehemosorption condition of the subcellular structures.

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In combination of the ulcer disease and pancreatitis with the aim to achieve simultaneous suppression of gastric hypersecretion and reduction of the secretory pancreatic activity, a method of operation--selective proximal vagotomy added by cutting the celiac branch of the right vagal trunk has been developed. In 42 patients, operated on using the suggested method, the pancreatic secretion, acid production and gastric motility were studied. At observation of up to 7 years, the excellent and good results were noted in 88.

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