We study of seasonal variability of biochemical parameters of blood serum in female cynomolgus macaques (Macaca fascicularis) in the Adler nursery of the Research Institute of Medical Primatology kept under conditions of free access to the open enclosure. It was found that in the most favorable season for monkeys (from June to September) the serum levels of sodium, phosphorus, creatinine were significantly increased and cholesterol and calcium concentrations and lactate dehydrogenase activity were significantly reduced. There was no seasonal variability in the content of triglycerides, urea, potassium, activity of γ-glutamyltransferase, ALT, and AST.
View Article and Find Full Text PDFIntroduction: Rubella virus has pronounced teratogenic properties that can cause generalized and persistent intrauterine infection of the fetus. As a result, the control of the loss of teratogenicity inherent in «wild-type» virus strains is a necessary stage of a preclinical study of the vaccine strain for a live attenuated rubella vaccine.The purpose of the study is to comprehensively study the teratogenic properties of the vaccine strain of rubella virus «Orlov-V» in the experiment on rhesus macaques.
View Article and Find Full Text PDFObjectives: This study aimed to investigate the indications for and the results of axillary arterio-venous fistula in patients with a functionally single ventricle at mid-term follow-up after bidirectional cavopulmonary connection.
Methods: From 2012 to 2017, 20 patients aged 21.1 ± 8.
A relationship between transfer of monkeys from yard to individual cage and duration of stay in individual cage and the serum biochemical parameters is detected in Macaca mulatta males.
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