Publications by authors named "I Hinterseher"
Advanced bioinformatics analysis, such as systems biology (SysBio) and artificial intelligence (AI) approaches, including machine learning (ML) and deep learning (DL), is increasingly present in stem cell (SC) research. An approximate timeline on these developments and their global impact is still lacking. We conducted a scoping review on the contribution of SysBio and AI analysis to SC research and therapy development based on literature published in PubMed between 2000 and 2024.
View Article and Find Full Text PDF[Recommendations for the specialist further training of nursing personnel on intensive care units in the treatment of abdominal aortic aneurysms: results of a modified Delphi procedure with experts].
Chirurgie (Heidelb)
May 2024
Article Synopsis
- - The advancements in treating abdominal aortic aneurysms over the last 15 years have led to the need for a reassessment of the quality assurance guidelines for nursing personnel training in intensive care in Germany, which currently mandates a 50% specialist training quota that lacks empirical backing.
- - A diverse group of 37 experts participated in a modified Delphi process involving literature searches, surveys, and discussions to assess and redefine training quotas for nursing staff, ultimately reaching a consensus.
- - The expert panel recommended lowering the required specialist training quota to 30% and emphasized the need for structured programs to maintain and elevate nursing staff qualifications in intensive care units managing abdominal aortic aneurysms.
Article Synopsis
- * The most studied cell types were multipotent mesenchymal stromal/stem cells (MSCs), which showed a significant reduction in COVID-19 mortality risk (RR=0.63) across 24 published trials, supporting previous findings of MSC therapy's benefits.
- * The study emphasizes the diverse sources and methods of MSC manufacturing and delivery, highlighting the need for standardized practices and the establishment of a global registry for MSC clinical studies to enhance comparability
The gut microbiome plays a major role in human health, and gut microbial imbalance or dysbiosis is associated with disease development. Modulation in the gut microbiome can be used to treat or prevent different diseases. Gut dysbiosis increases with aging, and it has been associated with the impairment of gut barrier function leading to the leakage of harmful metabolites such as trimethylamine (TMA).
View Article and Find Full Text PDFArticle Synopsis
- The study looked at how well patients with leg problems followed exercise training and why some didn’t join in.
- Most patients felt they weren't given enough information about the benefits of walking exercises, even though many believed it could help them walk further without pain.
- The results show that doctors and patients need to communicate better about the importance of exercise for improving health.