Publications by authors named "I H J T De Hingh"

Introduction: Screening for colorectal cancer has been implemented to improve cancer-specific survival. This study aims to compare patient- and tumor characteristics, treatment, and survival between patients with screen-detected and clinically detected synchronous colorectal peritoneal metastases (CPM) in a Dutch population-based cohort.

Methods: Data from the Netherlands Cancer Registry (NCR) were used.

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Article Synopsis
  • Diagnostic imaging is crucial for treating ovarian and colorectal cancer by helping choose the best treatment options and assessing risks associated with them.
  • A joint guideline was created by multiple medical societies to address challenges in detecting and reporting peritoneal metastases, using literature reviews and consensus methods.
  • The consensus outlines key recommendations for best practices in imaging techniques, ensuring effective communication of results, and supporting clinical decisions regarding operability and treatment monitoring in affected patients.
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Article Synopsis
  • The study aimed to assess treatment outcomes, overall survival (OS), and factors influencing OS in patients with T1 ampullary cancer, a rare type of gastrointestinal cancer.
  • Out of 244 patients with clinical T1 ampullary cancer, 75% underwent surgery, but a significant number were found to have more advanced disease upon further examination.
  • The results indicated a stark difference in survival based on disease classification, with poor prognostic factors including higher pathological N classification and poorly differentiated tumors, emphasizing the need for aggressive treatment like pancreatoduodenectomy for T1 cases.
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Colorectal peritoneal metastases (CPM) are common in colorectal cancer patients. This article aims to provide GRADE guidelines for the use of hyperthermic intraperitoneal chemotherapy (HIPEC) in two clinical situations: (1) To determine the value of adjuvant HIPEC for the prevention of CPM in high-risk colorectal cancer patients; (2) to determine the impact on survival of cytoreductive surgery and HIPEC followed by adjuvant systemic chemotherapy as compared to systemic chemotherapy alone in patients with CPM.

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