Publications by authors named "I Gregory"
Cyanogenic plants can release toxic hydrogen cyanide (HCN) to defend against herbivory by hydrolyzing the cyanogenic glycosides (CNGs) with its β-glucosidases (β-GLUs). Numerous studies have speculated this CNG-mediated toxicity by a plant-pest interaction manner. However, the specific toxic effect of HCN was not well-demonstrated because of the interference of other ingested metabolites.
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- - The study aimed to create and validate machine learning models to predict failure of high-flow nasal cannula (HFNC) therapy in COVID-19 patients, while comparing these models to the traditional ROX index and examining accuracy across different races.
- - Conducted as a retrospective cohort study at four Emory University hospitals, it analyzed data from 984 adult COVID-19 patients who received HFNC therapy, identifying that 32.2% experienced HFNC failure.
- - The eXtreme Gradient Boosting (XGB) model showed superior performance (AUROC of 0.707) compared to the ROX index (AUROC of 0.616), but also highlighted significant racial disparities in prediction accuracy, which were less pronounced