STATUS OF THE COMPOSITION OF ALLERGENIC EXTRACTS FOR SKIN TESTING IN UKRAINE AND THE WAYS TO OPTIMIZE IT.

Objective was to to analyze the protein components of extracts of diagnostic allergens made in Ukraine in order to determine the next steps for their standardization. Electrophoresis in polyacrylamide gel was used to obtain electrophoregrams of Acarus siro, Dermatophagoides farinae, Dermatophagoides pteronyssinus, Alnus glutinosa, Betula pendula, Carpinus betulus, Ambrosia artemisiifolia, Artemisia absinthium, Dactylis glomerata, Festuca pratensis, Helianthus annuus, Lolium perenle, Poa pratensis, Secale cereale, Zea mays, cat hair, dog hair, sheep allergens, and allergen of feather pillows. The official site for the systematic nomenclature of allergens approved by the World Health Organization and the International Union of Immunological Societies was used to identify allergenic components.

DIAGNOSTIC PARAMETERS OF IN VIVO (SKIN PRICK) AND IN VITRO (ELISA) TESTS FOR DETERMINATION OF EPIDERMAL CAT AND DOG ALLERGENS SENSITIZATION IN PATIENTS WITH ALLERGIC RHINITIS AND ATOPIC ASTHMA.

Objective was to study and compare the parameters of the specificity and sensitivity of skin testing and serologic determination of specific cat and dog IgE. 88 patients with allergic rhinitis and / or asthma were examined by three different methods of specific allergic diagnosis (in vivo and in vitro) in accordance with the guidelines of the ethics committee of the National Pirogov memorial medical university, all were beyond the acute period. The inclusion criteria were allergic rhinitis diagnosis (both intermittent and persistent) and \ or asthma.