Publications by authors named "I Gherman"
Article Synopsis
- * A case is presented of a patient with no prior health issues who experienced severe complications after a C-section, leading to a diagnosis consideration of either amniotic fluid embolism or anaphylaxis immediately following delivery.
- * Timely recognition and differentiation between these two conditions are crucial for effective treatment, and the patient ultimately recovered and was discharged after three days in the hospital.
Following an outbreak of in Wales in July 2021 associated with sheep meat and offal, further genetically related cases were detected across the UK. Cases were UK residents with laboratory-confirmed in the same 5-single-nucleotide polymorphism (SNP) single-linkage cluster with specimen date between 01/08/2021-2031/12/2022. We described cases using routine (UK) and enhanced (Wales only) surveillance data.
View Article and Find Full Text PDFPharyngoesophageal diverticula are a rare anatomical abnormality and are classified in 3 types based on the area of their protrusion: Zenker diverticulum is the most common, followed by Killian-Jamieson diverticulum and the rarest, Laimer diverticulum. We report a case of a 68-year-old man who presented to our clinic with a 3-year history of moderate anemia uncovered after routine blood tests, progressive dysphagia for solids and food bolus impactions resolved spontaneously. Upper endoscopy revealed a wide-mouthed diverticulum, measuring 2-3 cm, with normal mucosa and food residue inside, just below the upper esophageal sphincter, on the left side of the esophageal wall and also hiatal hernia with diffuse mucosal bleeding.
View Article and Find Full Text PDFArticle Synopsis
- Mechanistic models have traditionally been used to illustrate complex biological processes, but their increasing complexity has raised computational challenges for simulations and real-time analysis.
- Surrogate machine learning (ML) models can provide a more efficient approximation of these complex models, significantly reducing computational requirements once they are trained.
- The paper reviews existing literature on ML surrogates, focusing on their design, training, and practical applications in biological modeling, suggesting their potential to enable complex biological system simulations on standard computer setups.
Bacillus cytotoxicus is a member of the Bacillus cereus group with the ability to grow at high temperatures (up to 52℃) and to synthesize cytotoxin K-1, a diarrhoeagenic cytotoxin, which appears to be unique to this species and more cytotoxic than the cytotoxin K-2 produced by other members of this group. Only a few isolates of this species have been characterized with regard to their cytotoxic effects, and the role of cytotoxin K-1 as a causative agent of food poisoning remains largely unclear. Bacillus cytotoxicus was initially isolated from a food-borne outbreak, which led to three deaths, and the organism has since been linked to other outbreaks all involving plant-based food matrices.
View Article and Find Full Text PDF