Clinically Significant and Germline Variants in Breast Cancer-A Single-Center Experience.

Background: Conditions associated with pathogenic (PVs) or likely pathogenic variants (LPVs) are often severe. The early detection of carrier status is ideal, as it provides options for effective case management.

Materials And Methods: The study involved 58 patients with a personal and familial history of breast cancer (BC) who underwent genetic testing at the Regional Centre for Medical Genetics Dolj over a three-year period.

Basal Cell Carcinoma-A Retrospective Descriptive Study Integrated in Current Literature.

Basal cell carcinoma (BCC) is considered to be the most common cancer in humans. It has a slow growth rhythm, and for this reason, metastases are rare. For our retrospective study, we selected 180 patients from those who underwent surgery for a variety of skin tumours between January 2019 and August 2022 and whose histopathological examination revealed basal cell carcinoma.

Retrograde urethrosonography with SonoVue in strictures of the male urethra: a pilot study.

Aim: To evaluate the effectiveness of SonoVue urethrosonography in diagnosing the adult male anterior urethral strictures pathology in comparison with retrograde urethrography.

Material And Method: We standardised the method and performed a comparative study evaluating the diagnosis of urethral strictures using retrograde urethrography and retrograde ultrasonographic exploration with SonoVue on 6 male patients.

Results: In all patients, the existence of urethral stricture, localization and its extension were confirmed.

Ultrasound as the first imaging method in severe lung disease. Considerations about a case of pulmonary tuberculosis and review of the literature.

Abdominal ultrasound (US) performed as a "primary imaging procedure" is an important diagnostic tool in gastroenterol-ogy. Expanding the routine investigation to the lower thoracic region might sometimes accelerate the diagnosis in inconclusive manifestations such as pulmonary pathology.US is a valuable tool in evaluating patients with breathing difficulties, chest pain, hypoxia, or chest trauma.

A reactor designed for the ultrasonic stimulation of enzymatic esterification.

A laboratory scale ultrasonic flow reactor capable of enhancing enzymatic reactions has been built and characterized using as a model reaction the enzymatic synthesis of isoamyl acetate using Lipozyme 435 immobilized on a macroporous anion exchange resin. The efficiency of the reactor was determined in relation to ultrasonic power density (measured by 4-nitrophenol dosimetry), position of ultrasonic horn and temperature. The results show that ultrasound can enhance the process efficiency and also reduce the reaction time.