[ASSOCIATION OF FIBROBLAST GROWTH FACTOR 23 WITH MARKERS OF INFLAMMATION AND FIBROSIS IN DIABETIC NEPHROPATHY].

The aim of the present study was to establish the disorders of mineral metabolism and production of monocyte chemoattractant protein type 1 (MCP-1) and plasminogen activator inhibitor type 1 (PAI-1) in patients with diabetic nephropathy (DN) at different stages of the disease. We examined 78 patients with DN aged from 57 to 76 years. Fibroblast growth factor 23 (FGF23), MCP-1 and PAI-1 levels in blood serum were determined by ELISA.

Features of endothelium morphological structure in kidney vessels, coronary arteries and aorta during chronic kidney disease.

Objective: Introduction: Vascular endothelium function interruption has the main role among mechanisms of development and progression of chronic kidney disease. In numerous experimental and clinical studies, it was proved that activated vascular endothelium is a structural and functional unit that matches processes of inflammation with intravascular coagulation, fibrinolysis and haemorheological disorders. The aim: To identify special features of endothelium morphological structure in kidney vessels, coronary arteries and aorta during chronic kidney disease.

[Habituation of evoked potentials in subjects with high, medium and low levels of anxiety].

The habituation of the peak-to-peak amplitudes of N1P2 and P2N2 complexes of the evoked potentials as responses to series of the increasing number of visual and acoustic stimuli was investigated in 55 male and female volunteers aged 20-30. The size and speed of the habituation process were approximated by hyperbola. The shape and coefficients of the hyperbola were correlated with high, medium and low levels of the anxiety and probably reflected the balance between synchronization and desynchronization processes in the cortex.

[Programmed death of the eukaryote cells].

The authors review literary and own data on programmed death of cells (PDC) in animals and plants, molecular mechanisms of apoptosis in animals, and key PDC regulating genes.

[The status of the progeny of male rats subjected to low-dose external gamma irradiation exposure].

In studies on 120 mature males of Wistar rats and 252 female rats of the same line, 20-day-old fetuses and 974 young rats of the first generation, anomalies of antenatal and postnatal development were found after exposure of spermatids and spermatozoa to gamma-radiation in doses 0.25-1.0 Gy.