[The immunological diagnosis of peptostreptococcal infection].

The work deals with different methods for the diagnosis of anaerobic streptococcal infection, experimentally tested and clinically approved in the examination of children with acute pneumonia. The passive hemagglutination test, the immune rosette formation test and the specific lymphocyte blastogenesis test were used for diagnosis. As sensitin and antigen, the preparation of the peptostreptococcal bacterial mass was used.

[Immunologic status of children living in a region with an increased level of nitrates in the drinking water].

Practically healthy schoolchildren living in the district with a high content of nitrates in drinking water experienced distinct quantitative and functional changes of immune indicators: violation of the ratio of immunoregulatory lymphocyte subpopulations, the high level of spontaneous T-lymphocyte blastogenesis, IgE-hyperglobulinemia. The above changes of the immune system could indicate both body sensitization and its desadaptation under unfavourable conditions.

[Effect of metronidazole on the course of experimental anaerobic streptococcal pneumonia].

The effect of metronidazole in experimental anaerobic pneumonia in guinea pigs infected with peptostreptococci has been studied. In the untreated animals the prolonged pathological process in the lungs is mainly associated with the suppression of the functional state of the thymus-dependent link of the immune system. Metronidazole suppresses anaerobic flora, stimulates local immune reaction and arrests the development of inflammatory changes in the lungs.