Publications by authors named "I G Rekhtina"
Article Synopsis
- The study aimed to analyze bleeding and clotting complications in patients with systemic AL-amyloidosis, focusing on their relation to lab results reflecting hemostasis.
- In a group of 40 newly diagnosed patients, significant findings included that 50% showed skin and mucosal bleeding, while 17.5% had thrombotic events before therapy started, with a noted link between these two complications.
- The research highlighted that most patients with bleeding had concurrent hypercoagulation, particularly in cases with kidney damage, and overall, hypercoagulation was more prevalent compared to hypocoagulation among the patients.
Paraprotein is a laboratory biomarker of plasma cell tumors and other lymphoproliferative diseases. Its determination is necessary for diagnosing, monitoring and assessment of therapy effectiveness. The lecture presents the main methods of qualitative and quantative analysis of monoclonal proteins: gel electrophoresis, capillary electrophoresis, immunofixation and nephelometry features, possibilities and limitations are reviewed.
View Article and Find Full Text PDFOur case demonstrates severe bone disease in primary AL-amyloidosis without concomitant multiple myeloma. A 30-year-old man had spontaneous vertebral fracture Th8. A computed tomography scan suggested multiple foci of lesions in all the bones.
View Article and Find Full Text PDFAim: To assess the safety and efficacy of autologous haematopoietic stem cell transplantation (auto-HSCT) in multiple myeloma (MM) patients with dialysis-dependent renal failure.
Materials And Methods: During a period from May 2010 to December 2016 fourteen MM patients with dialysis-dependent renal failure aged 48 to 65 years underwent auto-HSCT. After the induction therapy complete response, very good partial response, partial response were documented in 64, 29, 7% of patients, respectively.