[Ability of a recombinant protein containing fragment 114-122 of myelin basic protein, to cause allergic encephalomyelitis in guinea pigs].

Four genetic constructions have been designed, capable of producing in E. coli the hybrid beta-galactosidases containing the encephalitogenic determinant 114-122 of myelin basic protein. The ability of chromatography-purified proteins to cause allergic encephalomyelitis in guinea pigs has been investigated.

[Pharmacological analysis of the effect of natural double-helical nucleic acids on the detoxifying function of the liver].

The effect of interferon inductors i.e. double stranded RNAs from S.

[Toxic properties of the double-stranded RNA of virus-like particles from Saccharomyces cerevisiae killer yeasts].

The toxic properties of dsRNA isolated from S. cerevisiae were studied on noninbred albino mice. The preparation was administered intraperitoneally.

[Acute toxicity and cumulative properties of poly(I).poly(C) and poly(G).poly(C) polyribonucleotide complexes].

Acute experiments on mice and rats were made to determine the intraperitoneal lethal doses of the polyribonucleotide complexes poly (I).poly (C) and poly (G).poly (C) manufactured in this country.