Publications by authors named "I G Kozlova"

Cell adhesion molecules (CAMs) are cell surface glycoproteins mediating interactions of cells with other cells and the extracellular matrix. By mediating the adhesion and modulating activity of other plasma membrane proteins, CAMs are involved in regulating a multitude of cellular processes, including growth, proliferation, migration, and survival of cells. In this review, we present evidence showing that various CAMs interact with the epidermal growth factor receptor (EGFR), a receptor tyrosine kinase inducing pro-proliferative and anti-apoptotic intracellular signaling in response to binding to several soluble ligands, including the epidermal growth factor.

View Article and Find Full Text PDF

Purpose: This study assesses the impact of preoperative administration of Oku-Oku eye drops on the severity of conjunctival hyperemia and the risk of hemorrhagic complications in the early postoperative period following glaucoma surgery.

Material And Methods: The study included a group of 30 patients (30 eyes) with uncontrolled primary open-angle glaucoma who underwent non-penetrating deep sclerectomy. The main group included 15 eyes, in which Oku-Oku drops were administered twice - on the day before surgery (upon hospital admission) and immediately before the operation.

View Article and Find Full Text PDF
Article Synopsis
  • Equine piroplasmosis (EP) is a serious global infection that can be fatal to horses, with this study focusing on its presence in Siberia, Russia, where data was previously lacking.
  • Blood samples from 750 horses across three regions in Siberia revealed that Theileria equi was present in 60.4% and Babesia caballi in 7.2% of the samples, indicating a significant prevalence of these pathogens.
  • Genetic analysis showed T. equi was mainly of two genotypes, while B. caballi exhibited high genetic diversity with seven variants found, leading to the identification of new genetic clusters that have broadened existing knowledge about this pathogen's diversity.
View Article and Find Full Text PDF

Purpose: This study assesses the light sensitivity and its variability in each point of the visual field in patients without glaucoma and with different stages of glaucoma.

Material And Methods: The data of a prospective analytical case-control study involving 500 patients were analyzed. The initial examination of all patients was performed using basic ophthalmological methods, including static perimetry.

View Article and Find Full Text PDF