Publications by authors named "I G Kirvalidze"

Coronary heart disease (CHD) is the most common cause of human mortality. Despite of recent advances in the management of CHD (drug treatment, coronary angioplasty and stenting, coronary artery bypass surgery) prognostic estimation of this kind of mortality threatens to increase to the year 2030. Major cause of adversity of CHD is decrease in myocardial contractility which leads to heart failure (HF).

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An article reviews etiopathogenesis of cardiomyopathy. Regardless of the fact that many early days' fundamental investigations are devoted to cardiomyopathy problem, still there is no common consideration concerning the etiology, pathogenesis, morphogenesis, classification and therapy of cardiomyopathy as well. Problem concerning the etiology of cardiomyopathy appear of particular interest.

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Investigation of ethiology, pathogenesis, morphogenesis, pathokinesis, treatment and prevention of cardiomyopathy is one of the most important problems of cardiology. Last years many scientific forums have been devoted to cardiomyopathy problems and still many issues remain disputable and needs further investigation and definition. In particular, investigation of metabolic processes in cardiac muscle seems of great importance.

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