Publications by authors named "I G Demarchi"
Clinical practice guidelines (CPGs) and consensus-based recommendations (CBRs) require considerable effort, collaboration, and time-all within the constraints of finite resources. Professional societies, such as the International League Against Epilepsy (ILAE), must prioritize what topics and questions to address. Implementing evidence-based care remains a crucial challenge in clinical practice.
View Article and Find Full Text PDFEnvelope Protein in Differential Serodiagnosis of Dengue, Zika, and Chikungunya Viruses: A Systematic Review.
Curr Top Med Chem
October 2024
Objectives: This systematic review was conducted to evaluate the applicability of the envelope (E) protein in the diagnosis of arboviruses.
Methods: This review was performed in accordance with the PRISMA statement. Five databases were explored (PubMed, Web of Science, Scopus, EMBASE, and IEDB).
Article Synopsis
- - The International League Against Epilepsy's (ILAE) Task Force created recommendations for diagnosing and treating anxiety and depression in kids with epilepsy after reviewing studies on screening measures and treatment effectiveness.
- - Key recommendations for diagnosis include universal screening, closer monitoring for high-risk children, and using multiple sources to assess symptoms while emphasizing the importance of recognizing symptoms for better treatment outcomes.
- - For treatment, individualized plans are advised, with monitoring for mild cases and referrals for more severe conditions, alongside the development of clinical care pathways and age-appropriate psychosocial interventions.
Thiazolidines derivatives and their anti-inflammatory activity in LPS-induced RAW 264.7 macrophages: a systematic review and meta-analysis.
Nat Prod Res
August 2024
Thiazolidine scaffolds have been investigated for decades, due to their wide range of biological activity. In this way, the main objective of this systematic review was to elucidate the anti-inflammatory activity of thiazolidine derivatives against nitric oxide (NO) production in lipopolysaccharide (LPS)-induced RAW 264.7 macrophages.
View Article and Find Full Text PDFPrimary studies have demonstrated that despite being useful, most of the drug-drug interaction (DDI) alerts generated by clinical decision support systems are overridden by prescribers. To provide more information about this issue, we conducted a systematic review and meta-analysis on the prevalence of DDI alerts generated by CDSS and alert overrides by physicians. The search strategy was implemented by applying the terms and MeSH headings and conducted in the MEDLINE/PubMed, EMBASE, Web of Science, Scopus, LILACS, and Google Scholar databases.
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