Publications by authors named "I G Burwash"
Article Synopsis
- Severe aortic stenosis (AS) is identified by a specific heart murmur pattern and a weak or absent second heart sound.
- Diagnosing AS severity involves echocardiography to assess blood flow and aortic valve area, which helps determine the need for treatment.
- The guide provides strategies for using various imaging techniques to accurately diagnose and evaluate the progression of AS, especially when measurements are inconsistent.
Background: In patients with low-gradient (LG) aortic stenosis (AS), confirming disease severity and indication of intervention often requires dobutamine stress echocardiography (DSE) or aortic valve calcium scoring by computed tomography. We hypothesized that the mean transvalvular pressure gradient to effective orifice area ratio (MG/EOA, in mm Hg/cm) measured during rest echocardiography identifies true-severe AS (TSAS) and is associated with clinical outcomes in patients with low-flow, LG-AS.
Objectives: The purpose of this study was to evaluate the diagnostic and prognostic value of MG/EOA ratio.
Computational simulation model of transcatheter edge-to-edge mitral valve repair: a proof-of-concept study.
Eur Heart J Cardiovasc Imaging
September 2024
Aims: As transcatheter mitral valve (MV) interventions are expanding and more device types and sizes become available, a tool supporting operators in pre-procedural planning and the clinical decision-making process is highly desirable. We sought to develop a finite element computational simulation model to predict the results of transcatheter edge-to-edge repair (TEER) interventions.
Methods And Results: We prospectively enrolled patients with secondary mitral regurgitation (MR) referred for a clinically indicated TEER.
Cost-effectiveness of population screening for aortic stenosis.
Eur Heart J Qual Care Clin Outcomes
May 2024
Background And Aims: Aortic stenosis (AS) is a progressive disease predominantly affecting elderly patients that carries significant morbidity and mortality without aortic valve replacement, the only proven treatment. Our objective was to determine the cost-effectiveness of AS screening using transthoracic echocardiography (TTE) in a geriatric population from the perspective of the publicly funded healthcare system in Canada.
Methods: Markov models estimating the cost-effectiveness ratio (ICER) for AS screening with a one-time TTE were developed.