Publications by authors named "I G Boldina"

Brain samples were collected from 514 voles and wild mice in Estonia, and examined for rabies. The samples were tested with antigen ELISA, and 8.6% of them additionally by virus isolation assay.

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Clinical investigations performed in 735 patients have shown that in addition to the improvement of organisation of the medical aid and the universally recognized resuscitation measures for trauma shock, the prophylactics and treatment of intoxication, metabolic, immune and other disorders developing in the patients soon after trauma should be started as early as at the prehospital step.

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We compared 24 rabies samples collected in Estonia in 1989 to 1992, to identify the kinds of rabies strains circulating in this country. Eleven of the strains came from the islands of Saaremaa, Hiiumaa and Muhu, off the Baltic coast; 13 came from the mainland. The mainland strains, like those from the 1988 to 1989 epizootic in Finland, were antigenically different from the 11 island isolates.

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State of energy metabolism was studied in brain of rats at agonal steps caused by bleeding during severe and long-term hypotension (30 mmHg, up to 30 hrs). Fast loss of high energy-containing phosphates, cell energy potential of adenine nucleotides and an increase in the lactate/pyruvate ratio were found in non-resistant rats. At the same time, in the most resistant rats normal content of creatine phosphate, ATP was maintained; energy potential was unaltered and anaerobic glycolysis was not activated.

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