Publications by authors named "I Fukunaga"

Article Synopsis
  • Clinical research typically requires careful study designs that account for variables like sex and age, but often overlooks body size factors like height and weight in neuroimaging studies.
  • This study analyzed data from 267 healthy adults to explore how body height and weight relate to various brain and spinal cord MRI metrics, finding significant correlations, especially with brain gray matter volume and cervical spinal cord area.
  • The results suggest that body size is an important biological variable that should be included in clinical neuroimaging study designs to enhance accuracy in understanding brain and spinal cord structures.
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Associating values to environmental cues is a critical aspect of learning from experiences, allowing animals to predict and maximise future rewards. Value-related signals in the brain were once considered a property of higher sensory regions, but their wide distribution across many brain regions is increasingly recognised. Here, we investigate how reward-related signals begin to be incorporated, mechanistically, at the earliest stage of olfactory processing, namely, in the olfactory bulb.

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Spike timing-based representations of sensory information depend on embedded dynamical frameworks within neuronal networks that establish the rules of local computation and interareal communication. Here, we investigated the dynamical properties of olfactory bulb circuitry in mice of both sexes using microelectrode array recordings from slice and in vivo preparations. Neurochemical activation or optogenetic stimulation of sensory afferents evoked persistent gamma oscillations in the local field potential.

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Article Synopsis
  • - The study aimed to assess a new imaging technique, 3D-QALAS, for measuring brain tissue properties (T1, T2, and proton density) using different MRI machines without being tied to a specific brand.
  • - Conducted on various 3T MRI systems with healthy volunteers and multiple sclerosis patients, the results showed high accuracy and reproducibility of measurements across different machines and conditions.
  • - The findings indicate that 3D-QALAS can effectively provide consistent brain tissue mapping regardless of the MRI vendor, making it a promising tool for clinical applications.
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