Publications by authors named "I Fuertes"
Article Synopsis
- - The study analyzed the survival rate and interruption risks of adalimumab (ADA) treatment in 539 adult patients with hidradenitis suppurativa (HS), providing insights before and after the COVID-19 pandemic.
- - Findings revealed that about 39.92% of patients interrupted ADA, with the main reasons being inefficacy (51.69%) and adverse effects (21.35%); ADA showed a median overall drug survival of 56.2 months.
- - Factors like female gender, prolonged HS diagnosis, and higher HS severity correlated with decreased ADA survival, while post-pandemic trends included younger patients starting treatment at a lower HS stage.
Article Synopsis
- The study focuses on defining and characterizing the disease phenotypes of adult patients with undifferentiated autoinflammatory diseases who experienced recurrent fevers and inflammatory issues, with inconclusive genetic tests.
- It analyzed 134 patients from a reference center over several years, identifying five phenotypes, including a significant number meeting the criteria for PFAPA syndrome and several with varying predominant symptoms.
- The treatment analysis found that medications like prednisone, colchicine, and anakinra were commonly prescribed, with effectiveness rates of 41.3%, 40.2%, and 58.3% for complete responses, respectively, with specific preferences for medications based on patient phenotype.
Insect physiology and reproduction depend on several terpenoid compounds, whose biosynthesis is mainly unknown. One enigmatic group of insect monoterpenoids are mealybug sex pheromones, presumably resulting from the irregular coupling activity of unidentified isoprenyl diphosphate synthases (IDSs). Here, we performed a comprehensive search for IDS coding sequences of the pest mealybug .
View Article and Find Full Text PDFArticle Synopsis
- * Out of 9,927 people diagnosed with a bacterial STI, 1,690 had multiple episodes, highlighting a significant prevalence of reinfection.
- * Key risk factors for repeated infections included being assigned male at birth, being under 34 years old, identifying as part of the gay, bisexual, or transgender community, and having initial diagnoses of gonorrhea or LGV, as well as coinfection with HIV.
Background: Since May, 2022, a large global outbreak of human mpox (formerly known as monkeypox) has predominantly affected men who have sex with men. The strain responsible, Clade IIb, has mutated substantially from precursors originating from the 2017-18 outbreak in Nigeria. Immunity to smallpox, another orthopoxvirus, via previous infection or vaccination provides lifelong immunity.
View Article and Find Full Text PDF