Publications by authors named "I Fierro"
Article Synopsis
- An observational study involving 71 participants revealed that those with certain personality traits—like antisocial and obsessive-compulsive tendencies—are more active physically, suggesting that personality may influence coping strategies through exercise.
- Results show that individuals in the study had significantly lower scores in various personality traits compared to the general population, indicating unique psychological profiles associated with problem gambling and their potential impact on engagement in physical activities.
In 2016 diabetes was declared an epidemic and a health emergency in Mexico. As the rationale of the treatment is to achieve target glycemia levels, the appropriateness of the medications used is important. The aim of this study is to learn the pattern of antidiabetic drug prescription and factors associated with inappropriate prescription in Mexico.
View Article and Find Full Text PDFBackground: Carbapenem-resistant , particularly isolates classified as sequence-type 258 (ST258), are multidrug-resistant strains that are strongly associated with poor-prognosis nosocomial infections, as current therapeutic options are limited and ineffective. In recent years, phage therapy has emerged as a promising treatment option for these scenarios.
Methodology And Results: We report the isolation and characterization of three new phages against ST258 strains recovered from Machángara river wastewater.
Background: High cytokine levels have been associated with severe COVID-19 disease. Although many cytokine studies have been performed, not many of them include combinatorial analysis of cytokine profiles through time. In this study we investigate the association of certain cytokine profiles and its evolution, and mortality in SARS-CoV2 infection in hospitalized patients.
View Article and Find Full Text PDFImpact of single-nucleotide variants and nutritional status on population pharmacokinetics of Doxorubicin, and its effect on cardiotoxicity in children with leukemia.
J Oncol Pharm Pract
September 2023
Purpose: Doxorubicin is an important antineoplastic agent with wide interindividual variability in response to treatment and in its cardiotoxic effects. To determine the effect of genotypic status of three single-nucleotide variants in , , and genes and nutritional status assessed by body mass index, on the population pharmacokinetics of Doxorubicin and its cardiotoxic effects in pediatric patients with leukemia.
Patients And Methods: Seventy pediatric patients treated with Doxorubicin were studied, in which 189 biological samples were obtained to determine Doxorubicin concentrations (1 to 3 samples per patient) at different times, for 20 h.