Publications by authors named "I Ferreira Montero"
Article Synopsis
- Natural products are vital in drug development due to increasing antibiotic resistance and the emergence of new diseases.
- Advancements in genome sequencing and bioinformatics have unveiled the biosynthetic capabilities of actinomycetes, leading to significant discoveries.
- A new biosynthetic gene cluster (BGC) related to diazo group formation was identified in a strain from leaf-cutting ants and was successfully activated to produce three compounds, named crexazones, with one being a novel structure.
Article Synopsis
- The study assesses emotional dysregulation in Chilean teachers, examining gender and age differences among a sample of 1059 educators, predominantly female.
- The research utilized the Difficulties in Emotional Regulation Scale (DERS-E) and confirmed the scale's validity and reliability through various analyses.
- Findings revealed notable emotional dysregulation differences based on gender and age, stressing the need for targeted training programs to enhance teachers' emotional skills for improved educational environments.
Technological advances in studying the human microbiome in depth have enabled the identification of microbial signatures associated with health and disease. This confirms the crucial role of microbiota in maintaining homeostasis and the host health status. Nowadays, there are several ways to modulate the microbiota composition to effectively improve host health; therefore, the development of therapeutic treatments based on the gut microbiota is experiencing rapid growth.
View Article and Find Full Text PDFUnlabelled: Latin America presents a high prevalence of Helicobacter pylori(Hp) infection. Between1996-2003, the prevalence in Santiago, Chile, was 70%; recent studies indicate a decreasein this infection. Updating the frequency of Hp is crucial due to its associated health impact.
View Article and Find Full Text PDFPiperazic acid is a cyclic nonproteinogenic amino acid that contains a hydrazine N-N bond formed by a piperazate synthase (KtzT-like). This amino acid, found in bioactive natural products synthesized by non-ribosomal peptide synthetases (NRPSs), confers conformational constraint to peptides, an important feature for their biological activities. Genome mining of strains has been revealed as a strategy to identify biosynthetic gene clusters (BGCs) for potentially active compounds.
View Article and Find Full Text PDF