Publications by authors named "I Fawzy"
Nowadays, Egypt is treating the Nile River Water to produce drinking water, and this process generates large amounts of waste, around 635 million m annually, which is called water treatment plant sludge (WTPS). This WTPS cost the government around 30 million US dollars to return it back to the Nile River in addition to negatively affecting the environment. Therefore, there is an urgent need to find environmentally friendly alternatives that reduce the impact of such an issue.
View Article and Find Full Text PDFChemoresistance encountered using conventional chemotherapy demands novel treatment approaches. Asplatin (Asp), a novel platinum (IV) prodrug designed to release cisplatin and aspirin in a reductive environment, has demonstrated high cytotoxicity at reduced drug resistance. Herein, we investigated the ability of green-synthesized nanocarriers to enhance Asp's efficacy.
View Article and Find Full Text PDFArticle Synopsis
- The study evaluated the reliability and effectiveness of the Swimmer Arm-to-Shoulder (SAS) test to differentiate between shoulder impingement and cervical radiculopathy in patients with shoulder pain lasting up to 12 weeks.
- In a sample of 718 patients, the SAS test showed high accuracy, with a sensitivity of 89.2% and specificity of 96.1%, effectively identifying the underlying causes of shoulder pain.
- The results concluded that the SAS test is a simple, dependable tool for both screening and confirming diagnoses related to shoulder and cervical spine conditions.
Background: Proteoglycans are important tumor microenvironment extracellular matrix components. The regulation of key proteoglycans, such as decorin (DCN), by miRNAs has drawn attention since they have surfaced as novel therapeutic targets in cancer. Accordingly, this study aimed at identifying the impact of miR-181a in liver cancer and its regulatory role on the extracellular matrix proteoglycan, DCN, and hence on downstream oncogenes and tumor suppressor genes.
View Article and Find Full Text PDFBackground: Despite the advancements in extracorporeal membrane oxygenation (ECMO) technology, balancing the prevention of thrombosis and the risk of bleeding in patients on ECMO is still a significant challenge for physicians. This systematic review and meta-analysis aimed to assess the efficacy and safety of viscoelastic point-of-care (POC)-guided coagulation management in adult patients on ECMO.
Methods: PubMed Medline, Embase, Scopus, Web of Science, and Cochrane Library databases were searched.