Publications by authors named "I Fabiola Franco"

Purpose: Burnout is prevalent in radiation oncology (RO), and an increased focus on promoting physician wellness and formalizing wellness-directed efforts has transpired in recent years. We aimed to characterize current wellness leadership positions and efforts within academic RO departments.

Methods And Materials: Academic RO department chairs were contacted to inquire whether they had a departmental wellness leader with a request for leader contact information, if applicable.

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Objectives: To evaluate possible predictors of elevated postvoid residual volume (PVR) following onabotulinumtoxinA administration in patients with idiopathic overactive bladder (OAB), a condition that may include urinary urgency, frequency, and nocturia, without any identifiable cause or underlying neurological or metabolic condition.

Methods: Adults who had been treated with 100-200 U onabotulinumtoxinA for OAB and had previous failure of other OAB treatments were identified by retrospective review of medical chart data from three urology clinics in the United States treating patients with a variety of urological conditions. A total of 211 patients were allocated to cohorts based on posttreatment PVR < 200 mL (n = 173) and ≥ 200 mL (n = 38).

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Article Synopsis
  • Steatotic liver disease linked to metabolic dysfunction (MASLD) is prevalent in up to 30% of adults and is often associated with obesity and metabolic syndrome.
  • The study involved 42 patients split into three groups receiving different treatments: dietary advice only (CG), dietary advice plus aerobic exercise (AE + DA), and dietary advice plus high-intensity interval training (HIIT + DA).
  • Results showed that both exercise groups had significant reductions in cortisol levels, with HIIT + DA showing the greatest effects, and a notable decrease in hepatic steatosis was also observed, particularly in the AE + DA group.
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  • IBS and obesity can lead to alterations in the intestinal barrier, causing low-grade inflammation, which can be monitored using zonulin and intestinal fatty acid-binding protein (I-FABP) levels, along with urinary indican concentrations.
  • A 12-week Fitwalking program was tested on 57 mild IBS patients divided into obese, overweight, and normal weight groups, who walked three times a week, but no significant changes in most health metrics were found.
  • Despite limited changes in biochemical aspects, Fitwalking notably improved physical capacity in all groups and led to a decrease in inflammation levels, particularly in obese individuals, suggesting regular exercise may benefit gut health in this population.
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Irritable Bowel Syndrome (IBS) is a chronic functional gastrointestinal (GI) disorder characterized by abdominal pain, altered bowel habits, and bloating, affecting approximately 10.1% of the global population. While current treatments emphasize dietary modifications and symptom management, emerging evidence suggests that physical activity (PA) may help alleviate IBS symptoms.

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