Publications by authors named "I F DUFF"
Water beads are superabsorbent polymer balls. They were originally marketed for agricultural and decorative applications and are now sold as sensory toys. They can be harmful to children in 2 ways.
View Article and Find Full Text PDFPain after surgery causes significant suffering. Opioid analgesics cause severe side effects and accidental death. Therefore, there is an urgent need to develop non-opioid therapies for managing post-surgical pain.
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- Current guidelines suggest a personalized and combination approach to pain management, emphasizing the use of both drug and non-drug therapies, with a focus on reducing chronic pain risks in acute pain cases like surgery or trauma.
- Auricular vagus nerve stimulation (aVNS) is explored as a potentially effective non-drug therapy for managing both chronic and acute pain, with this study aiming to assess its clinical efficacy and safety.
- The analysis included 23 studies on chronic pain, 12 on acute postoperative pain, and 7 on experimental acute pain, finding significant pain reduction in chronic conditions through aVNS compared to sham treatments, indicating its potential effectiveness.
Article Synopsis
- * Research has shown that a product called Clarix Flo (FLO), derived from human amniotic membranes, can effectively reduce post-surgical pain in mice without the negative effects associated with opioids, by directly acting on pain-signaling neurons.
- * The study identified a purified component from human amniotic membrane, HC-HA/PTX3, which not only mimics the pain-relief effects of FLO but also works by altering neuron behavior to reduce pain, signaling the potential of biologics from birth tissues as a safer alternative for pain management.
Open and Percutaneous Trigeminal Nucleotractotomy: A Case Series and Literature Review.
Stereotact Funct Neurosurg
December 2023
Introduction: Nucleotractotomy is an efficient surgical technique that provides a high pain relief rate for specific clinical indications. There are two main approaches for performing this operation: an open and percutaneous technique.
Methods: In the Federal Center of Neurosurgery (Novosibirsk, Russia) from 2016 to 2022, 13 trigeminal nucleotractotomies (7 open and 6 percutaneous) were performed in 12 patients (5 women and 7 men).