Correction of the chemical composition effect on the activity measurement of gamma emitters in environmental samples at low energy.

If the sample and the calibration standard are identical in geometry and in density, many laboratories of radioactivity measurement using gamma spectrometry, do not proceed to the correction of the effect of the possible difference in chemical composition between them. Some laboratories proceed to the correction of this effect using the usual simple ratio between the self absorption factor of the sample and the calibration standard based on the linear attenuation coefficients obtained using transmission experiments. In this work we studied this question by conducting Monte Carlo simulation of several typical environmental samples with different chemical compositions.

Preliminary studies of acetylcholinesterase activity in the rat brain using N-phenylferrocenecarboxamide labelled by the technetium-99m.

There is currently great interest in developing radiolabeled substrates for acetylcholinesterase that would be useful in the in vivo imaging of patients with Alzheimer's disease. The reduction of acetylcholinesterase (AChE) activity in the brain has been measured in dementia disorders such as Alzheimer's disease and dementia with Lewy bodies using (11)C and (18)F-labeled acetylcholine analogues. Our aim was to develop a new 99mTc-labeled acetylcholine analogue: N-phenylferrocenecarboxamide labelled with technetium-99m (99mTc-TPCC) to study acetylcholinesterase activity.

Synthesis and evaluation of 99mTc-N-sulfanilamide ferrocene carboxamide as bacterial infections detector.

A technetium-99m-labeled derivative from sulfanilamide, further referred to as (99m)Tc-N-SFC, targeting infections in experimental animals, has been synthesized. The biological features of this radioactive agent have also been studied. The N-sulfanilamide ferrocene carboxamide (N-SFC) was chemically synthesized and then labeled with technetium-99m.