Publications by authors named "I Escapa"
Strains of two novel species were cultured from samples of human nostrils and skin collected in the United States and Botswana. These strains demonstrated growth on Columbia Colistin-Nalidixic Acid agar with 5% sheep blood and in liquid media (brain heart infusion and tryptic soy broth) supplemented with Tween 80, a source of the fatty acid oleic acid. Cells were Gram-positive, non-spore-forming, non-motile bacilli that showed catalase but not oxidase activity.
View Article and Find Full Text PDFArticle Synopsis
- Nasal colonization by certain bacteria increases infection risk, while others are linked to health; this study used human nasal epithelial organoids (HNOs) to explore these dynamics.
- HNOs were successfully colonized with three bacterial species for up to 48 hours, showing minimal harm and allowing for the bacteria to localize in the mucus.
- The research identified specific immune responses to the bacterial species, indicating that some bacteria trigger inflammation while others modulate immune signaling without causing infection.
has been postulated as a monophyletic group, whose precise position within the Gleichenoid families Dipteriaceae and Matoniaceae, remains poorly understood. Previously described specimens are based on frond fragments and its fertile morphology is represented by a few, poorly preserved specimens. We describe a new species based on the largest collection of fertile specimens known to date and discuss the evolutionary history of the genus based on the additional reproductive characters provided by the fossils described.
View Article and Find Full Text PDFArticle Synopsis
- Human nasal microbiota consist of various species that are generally linked to health, with certain species being more prevalent across different populations.
- A study examined 87 strains from Botswana and the USA, revealing that while some strains were geographically bounded, many others had wider distributions, and overall genomic structures were similar across species.
- The research found that these strains show little metabolic variation, with an exception in a USA strain lacking certain sulfate reduction genes, suggesting that coexisting strains might not effectively utilize distinct metabolic roles.
Article Synopsis
- Dolosigranulum pigrum is a beneficial bacterium linked to health indicators in human nasal microbiota, with potential therapeutic applications due to its positive health associations.
- Research on its genomic structure over 20 years revealed a stable chromosomal organization, closely related strains, and a diverse range of genetic elements that protect it from mobile genetic elements (MGEs).
- The study identified important defense mechanisms against MGEs, underscoring the bacterium's adaptability while maintaining genomic stability, making it a promising candidate for future health treatments.