Publications by authors named "I Erkin Acar"
Acute myeloid leukemia and myelodysplastic syndrome are both clonal hematologic malignancies that primarily affect older adults. Current treatments for AML/MDS are both limited in number and efficacy. This study aims to evaluate venetoclax-based therapies in AML/MDS, focusing on overall survival and recurrence-free survival rates, and to expand real-world data on its use.
View Article and Find Full Text PDFThe current research explored the dyadic relationships between general psychological distress (GPD) and coparenting dimensions (cooperation, conflict, triangulation) through the mediation of couple satisfaction among parents with young children. The sample comprised 184 heterosexual couples (184 mothers, 184 fathers, age range from 25 to 57 years) married for 10 years on average. The actor-partner interdependence model (APIM) and APIM Mediation Model analyses demonstrated significant relationships between mothers' and fathers' GPD and all three of their own coparenting dimensions (direct actor effects), also through their own couple satisfaction (indirect actor-actor effects).
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- - The study investigates how different cultural values influence parenting practices and child development by looking at the relationship between cultural dimensions, socialization goals, and parental beliefs about raising children.
- - Data from 865 mothers of toddlers across 14 countries were analyzed to explore how individualism vs. collectivism and other cultural traits relate to parenting styles that promote independence or interdependence.
- - Results showed mixed support for the hypotheses, revealing that while certain cultural traits like indulgence promote autonomy in parenting, traits like masculinity can negatively impact relational parenting approaches, highlighting the complexity of cultural influences on parenting.
It is estimated that only 0.02% of disseminated tumour cells are able to seed overt metastases. While this suggests the presence of environmental constraints to metastatic seeding, the landscape of host factors controlling this process remains largely unclear.
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- Polycystic ovary syndrome (PCOS) is a growing endocrine and metabolic disorder linked to inflammation and oxidative stress, characterized by symptoms such as high levels of androgens and insulin resistance.
- The study compared 30 PCOS patients to 30 healthy volunteers, measuring oxidative stress and inflammatory markers using various biochemical methods.
- Results showed that patients with PCOS had significantly lower total thiol and native thiol levels, while total antioxidant status, total oxidant status, and inflammatory markers were markedly higher compared to healthy individuals.