Enhancing Mental Health Treatment for Borderline Personality Disorder in Corrections.

Improving mental health among inmates has been a long-term challenge for correctional systems. Although borderline personality disorder (BPD) has garnered limited attention in the literature, evidence suggests it is highly prevalent in corrections. It is important to provide comprehensive treatment for this condition, given its high prevalence and significant personal, societal, and economic burden.

Effect on breathing of ventral medullary surface cooling in neonatal goats.

The present study was designed to determine whether neurons near the ventral medullary surface (VMS) that are important to control of breathing in adult mammals are also important to control of breathing in neonates. In 7-day-old goats (n = 22), the VMS was surgically exposed under halothane anesthesia. Stainless steel thermodes (2 x 2 mm) were used to cool (20 degrees C) and thereby create neuronal dysfunction of discrete VMS sites.

Patterns of glial development in the human foetal spinal cord during the late first and second trimester.

Although the presence of radial glia, astrocytes, oligodendrocytes and microglia has been reported in the human foetal spinal cord by ten gestational weeks, neuroanatomic studies employing molecular probes that describe the interrelated development of these cells from the late first trimester through the late second trimester are few. In this study, immunocytochemical methods using antibodies to vimentin and glial fibrillary acidic protein were used to identify radial glial and/or astrocytes. An antibody to myelin basic protein was used for oligodendrocytes and myelin; and, an antibody to phosphorylated high and medium molecular weight neurofilaments identified axons.

Neuroanatomical localization of myelin basic protein in the late first and early second trimester human foetal spinal cord and brainstem.

The temporal and spatial expression of myelin basic protein in the first and second trimester human foetal spinal cord and brainstem from 9 to 20 gestational weeks was determined by immunocytochemistry in sections of cervical, thoracic and lumbosacral levels from 41 human foetal spinal cords and ten brainstems. Myelin basic protein-positive oligodendrocytes were observed peripheral to the ependyma at 9-10 gestational weeks. Oligodendrocytes expressing myelin basic protein were seen at 10-12 gestational weeks in the anterior and lateral funiculi.