[Complications of arterial infusion of CDDP in the treatment of malignant neoplasms].

Arterial infusion of cis-diamminedichloroplatinum (CDDP) is an effective therapy for malignant neoplasms. Severe complications after this therapy in 298 patients with malignant tumors were reviewed in our institute from March 1982 to August 1989. Arteries infused with CDDP and the number of infusions were as follows: bronchial artery (a.

[Transcatheter embolization of the renal artery to treat massive retroperitoneal hemorrhage in long-term dialysis patients].

Acquired cystic kidney disease (ACKD) and renal tumors often develop in long-term dialysis patients. In addition, rupture of the cysts leading to hemorrhagic shock can be another serious complication. There are few reports on transcatheter arterial embolization for retroperitoneal hemorrhage caused by cyst rupture in chronic dialysis patients.

[Combined treatment of invasive bladder cancer by intra-arterial infusion chemotherapy of cisplatin with or without other anticancer agents and concurrent radiotherapy--initial response and side effects].

Fourteen patients with invasive bladder cancer were treated by bilateral internal iliac artery infusion of cisplatin, with or without other anticancer agents, and concurrent radiotherapy. Angiotensin II was simultaneously infused in 10 cases. Of the 14 patients, complete response and partial response were achieved in 9 (64%) and 3, respectively.

[A clinical study of intraarterial infusion therapy with CDDP for primary osteosarcoma].

Eleven patients with primary osteosarcoma were treated by intra-arterial infusion of cisplatin. Cisplatin (50-100 mg/m2) was infused slowly into tumor feeding artery or proximal-to-the-lesion artery. An antidote, sodium thiosulfate, was also administered intravenously in 10 cases and angiotensin II was simultaneously used in 2 cases.