Protein Interactome of Amyloid-β as a Therapeutic Target.

The amyloid concept of Alzheimer's disease (AD) assumes the β-amyloid peptide (Aβ) as the main pathogenic factor, which injures neural and other brain cells, causing their malfunction and death. Although Aβ has been documented to exert its cytotoxic effect in a solitary manner, there is much evidence to claim that its toxicity can be modulated by other proteins. The list of such Aβ co-factors or interactors includes tau, APOE, transthyretin, and others.

[Electroencephalography entropy and depression].

Objective: The study is devoted to finding the relationship between EEG entropy indices and depression, assessed using the Beck Depression Inventory.

Material And Methods: The experiments involved 42 people aged 20-25 years. Each of them completed the psychological tests of Beck (depression), Spielberger (anxiety), and Wasserman (frustration).

[Evoked Potentials on Faces Presented in Emotional Context].

Ability for face recognition is a key skill for our social behavior. A lot of attention is devoted to investigation of emotional faces and expressions perception, but issue of context influence on face recognition process is not so explored. In the current study subjects had watched emotional film fragment before their EEG were recorded during the task with photos of neutral faces: actors from the film and fillers (actors who didn't appear in the film).

Electrooculogram detection of eye movements on gaze displacement.

Changes in potential are known to occur in the orbital area during saccades. The sign of these changes depends on the position of the electrode and the direction of eye rotation, while their amplitude depends on the rotation angle. The patterns of potentials can be used to resolve the reverse task, i.

[Eye movement detection with the aid of the oculogram in shifting the gaze].

Eye saccades are accompanied by changes of ocular electric potential. The sign of these changes involves a function of electrode location and eye movement direction while an indicator of the rotation angle is the amplitude. Based on the spatial distribution of the ocular potential one can solve an inverse problem and recover eye movement trajectory to be used for on-line computer control.