Home Care Patient's Experiences and Medication Burden Related to High-Risk Medication Use: A Cross-Sectional Study.

Background: Age, polypharmacy and comorbidity are examples of known factors that increase the risk of adverse drug reactions in patients. The use of high-risk medication also entails a heightened risk of harm. There is currently no information available on the home care patients' experiences and medication burden experienced due to their high-risk medication use and how they manage their medication.

Redox Homeostasis and Molecular Biomarkers in Precision Therapy for Cardiovascular Diseases.

Precision medicine is envisioned as the future of cardiovascular healthcare, offering a more tailored and effective method for managing cardiovascular diseases compared to the traditional one-size-fits-all approaches. The complex role of oxidative stress in chronic diseases within the framework of precision medicine was carefully explored, delving into the cellular redox status and its critical involvement in the pathophysiological complexity of cardiovascular diseases (CVDs). The review outlines the mechanisms of reactive oxygen species generation and the function of antioxidants in maintaining redox balance.

Emerging Strategies in Drug Development and Clinical Care in the Era of Personalized and Precision Medicine.

In the ever-changing landscape of modern medicine, we face an important moment where the interplay of disease, drugs, and patients defines a new paradigm [...

Comparative study on the results of orthodontic diagnostics by using algorithms generated by Artificial Intelligence and simple algorithms.

Introduction: Artificial intelligence (AI) is computer-generated intelligence, as opposed to the natural intelligence of humans and some animals. Kaplan and Haenlein define AI as "the ability of a system to correctly interpret external data, to learn from such data and use what it has learned to achieve specific goals and tasks through a flexible adaptation". The term "artificial intelligence" is used colloquially to describe machines that mimic the "cognitive" functions that people associate with other human minds.

Circadian Rhythms, Chrononutrition, Physical Training, and Redox Homeostasis-Molecular Mechanisms in Human Health.

A multitude of physiological processes, human behavioral patterns, and social interactions are intricately governed by the complex interplay between external circumstances and endogenous circadian rhythms. This multidimensional regulatory framework is susceptible to disruptions, and in contemporary society, there is a prevalent occurrence of misalignments between the circadian system and environmental cues, a phenomenon frequently associated with adverse health consequences. The onset of most prevalent current chronic diseases is intimately connected with alterations in human lifestyle practices under various facets, including the following: reduced physical activity, the exposure to artificial light, also acknowledged as light pollution, sedentary behavior coupled with consuming energy-dense nutriments, irregular eating frameworks, disruptions in sleep patterns (inadequate quality and duration), engagement in shift work, and the phenomenon known as social jetlag.