FEATURES OF THE UBIQUITIN-PROTEASOME SYSTEM IN PATIENTS WITH CHRONIC KIDNEY DISEASE STAGE 5D.

The aim of the study was to assess the activity of the ubiquitin-proteasome system in patients with chronic kidney disease stage 5D (CKD5D) and its relationship with clinical and laboratory parameters. We examined 80 patients with CKD5D on hemodialysis (HD). The mean age was 51.

[Morphological characteristics and intracellular electrolytic composition of blood cells at surgeries on lower extremities arteries].

Morphological characteristics and trace and macroelement composition of blood cells flowing out of ischemic lower limb before, during and after reconstructive surgeries under different type of anesthesia. A total of 102 male patients aged 45 to 60 years with atherosclerotic occlusions of the arteries of the femoral-popliteal zone were included into the study. According to anesthesia type all the patients were divided into 3 groups: group 1 consisted of 34 patients operated under spinal anesthesia, 37 patients of group 2 underwent surgery under combined anesthesia (spinal anesthesia with intravenous sedation), 31 patients of group 3 - under total intravenous anesthesia with myoplegia and artificial pulmonary ventilation.

Features of Immune Status in Patients with Tetralogy of Fallot during Operative Treatment.

Twenty six patients with tetralogy of Fallot at the age from 1 to 3 years old were examined. All examined patients required surgical correction of heart defect and were operated under conditions of artificial circulation. All patients were in a status of relative compensation or subcompensation.

[Oxygen transport and immune status in patients with congenital valvular heart disease].

Oxygen transport, its metabolic maintenance and immune status were studied in 17 patients with congenital valvular heart disease (CVD) having compensated (n = 8, group 1) and decompensated (n = 9, group 2) defects of hemodynamics. CVD patients with decompensated central hemodynamics and progressing hypoxia had impaired compensatory rearrangement of oxygen transport system. Accumulation of intracellular lactate, low activity of basic energetic cycles of blood cells most evident in decompensated CVD was observed in both the groups.