Evaluation of Cisplatin as an electrochemotherapy agent for the treatment of incompletely excised mast cell tumors in dogs.

Background: Electrochemotherapy (ECT) couples the administration of anticancer drugs with the delivery of electric pulses that increase the drug uptake through the cell membranes, resulting in an improved efficacy.

Hypothesis: To evaluate the tolerability and efficacy of cisplatin (CDDP) as an ECT agent to prevent recurrence of incompletely resected mast cell tumors (MCTs).

Animals: Thirty-seven dogs.

Comparison between two defibrillation waveforms.

Two defibrillation waveforms, the chopped biphasic pulses and the constant current pulses, were assessed and compared. Two indices are introduced. The first one is the ratio between the delivered energy W and the energy W(0) of a rectangular pulse with the same duration and electric charge.

Electrochemotherapy treatment for bilateral pleomorphic rhabdomyosarcoma in a cat.

A 13-year-old male neutered cat was presented for the sudden growth of two nodular lesions close to the upper eyelid of both eyes. Fine-needle aspiration cytology was suggestive of mesenchymal neoplasia. The cat had conservative surgical excision in order to preserve the eyelids' functionality; however, the histopathological report came with a diagnosis of incompletely excised bilateral pleomorphic rhabdomyosarcoma.

Shock advisory system for heart rhythm analysis during cardiopulmonary resuscitation using a single ECG input of automated external defibrillators.

Minimum "hands-off" intervals during cardiopulmonary resuscitation (CPR) are required to improve the success rate of defibrillation. In support of such life-saving practice, a shock advisory system (SAS) for automatic analysis of the electrocardiogram (ECG) contaminated by chest compression (CC) artefacts is presented. Ease of use for the automated external defibrillators (AEDs) is aimed and therefore only processing of ECG from usual defibrillation pads is required.