Publications by authors named "I Dolapci"
Purpose: OXA-48 producing Klebsiella pneumoniae is an emerging threat and outbreaks due to specific sequence types have been commonly reported. Here, we report an outbreak due to multidrug-resistant ST395 K. pneumoniae ST395.
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- Urinary tract infections (UTIs) in children caused by E.coli, especially the O25b/ST131 strain, are concerning due to their increased virulence and resistance to antibiotics.
- A study analyzed 200 E.coli isolates from UTI cases in pediatric patients to assess their antimicrobial resistance, virulence factors, and phylogenetic groupings, aiming to improve UTI management strategies.
- The results revealed high resistance rates to commonly used antibiotics, highlighting the need for better diagnostic and treatment approaches for UTI in children.
Breast cancer is the most common cancer in women. The human epidermal growth factor receptor 2 (HER2) overexpressing subtype is related to poor prognosis with an aggressive phenotype and is reported as one of the most commonly seen subtypes. Trastuzumab is prevalently used as a treatment method for HER2+ breast cancer however, resistance to the drug frequently occurs following the treatment.
View Article and Find Full Text PDFInvestigation of the presence of Capnophilic bacteria in routine urine cultures.
Eur J Clin Microbiol Infect Dis
April 2023
Article Synopsis
- - The study focused on the rare Capnophilic Escherichia coli (CEC) strains found in urinary tract infections (UTIs), analyzing their incidence and features in patients.
- - Out of 8500 urine samples, only nine CEC isolates (0.11%) were identified, with three belonging to a specific clone (O25b-ST131) and displaying varying antibiotic resistance.
- - The researchers noted that isolating CEC strains is challenging due to their specific growth requirements and suggested that capnophilic incubation could be beneficial for patients with certain health conditions.
In view of the significant negative impact of biofilm-mediated infection on patient health and the necessity of a reliable phenotypic method to detect biofilm producers, this study aimed to demonstrate phenotypic and molecular biofilm formation in coagulase-negative staphylococci (CoNS) isolated from catheter related infections and to compare the methods used with each other. The study was also aimed to determine the biofilm eradication effect of vancomycin in order to guide for the treatment. For the detection of biofilm formation, a total of 154 CoNS clinical isolates of which 30 being causative agents of catheter related bloodstream infection (CRBSI) (isolated from both the catheter tip and blood cultures of 15 patients), 89 being isolated from peripheral blood cultures of patients without a central venous catheter (CVC) (13 of them were bloodstream infection agents, 76 of them were contaminant), and 35 being isolated as catheter colonizer, were screened by tissue culture plate (TCP), Congo red agar (CRA) method and polymerase chain reaction (icaA, icaD and IS256).
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