Publications by authors named "I Dewenter"
Antiresorptive therapy in combination with radiation results in enhanced risk for necrosis and associated complicatifions.
Oral Surg Oral Med Oral Pathol Oral Radiol
January 2025
Article Synopsis
- Patients treated with both antiresorptive medication and radiotherapy in the head and neck are at increased risk for developing complications such as jaw necrosis, fractures, and recurrence of conditions.
- The study involved 17 patients who were compared to larger control groups, revealing significant differences in outcomes, with those receiving combined treatment facing higher risks.
- The findings suggest that the combination of these treatments leads to a four-fold increase in recurrence risk and a higher likelihood of serious complications compared to patients receiving just one type of treatment.
Improved quality of life after Ibandronic acid infusion in patients suffering from diffuse sclerosing osteomyelitis of the jaw.
Med Oral Patol Oral Cir Bucal
November 2024
Article Synopsis
- A cross-sectional study investigated the impact of Ibandronic acid on quality of life in patients with diffuse sclerosing osteomyelitis, focusing on 34 subjective health parameters.
- 15 patients completed standardized questionnaires before and two weeks after receiving 6mg of Ibandronic acid, reporting various improvements.
- All patients noted significant enhancements in quality of life, including better oral health, reduced pain, improved fatigue and emotional functioning, as well as fewer speech and swallowing issues.
Unlabelled: Intra-flap recurrence after reconstruction is a possible complication in oral squamous cell carcinoma (OSCC) after curative resection and reconstruction with a free flap.
Abstract: This case report describes an intra-flap recurrence after tumor resection and reconstruction with a latissimus dorsi flap due to OSCC. We report a 58-year-old female patient who underwent curative resection of a squamous cell carcinoma in the oral cavity and submental area and reconstruction with a latissimus dorsi free flap.
Background: An estimated 20% of patients with oral and oropharyngeal squamous cell carcinoma (OOSCC) have micrometastases (Mi) or isolated tumor cells (ITC) in the cervical lymph nodes that evade detection by standard histological evaluation of lymph node sections. Lymph node Mi and ITC could be one reason for regional recurrence after neck dissection. The aim of this study was to review the existing data regarding the impact of Mi on the survival of patients with OOSCC.
View Article and Find Full Text PDFMedication-related osteonecrosis of the jaw (MRONJ) is a serious adverse reaction associated with antiresorptive drugs such as bisphosphonates and denosumab. When dealing with advanced and/or multiple MRONJ lesions undergoing surgical therapy, the extent of surgery is often a topic of discussion. The aim of this study was to identify the differences in bone density in and around the MRONJ lesion before and after surgical treatment to evaluate the needed surgical extend of the modelling osteotomy.
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