Microgliosis and neuronal proteinopathy in brain persist beyond viral clearance in SARS-CoV-2 hamster model.

Background: Neurological symptoms such as cognitive decline and depression contribute substantially to post-COVID-19 syndrome, defined as lasting symptoms several weeks after initial SARS-CoV-2 infection. The pathogenesis is still elusive, which hampers appropriate treatment. Neuroinflammatory responses and neurodegenerative processes may occur in absence of overt neuroinvasion.

Behavior of heptavalent technetium in sulfuric acid under α-irradiation: structural determination of technetium sulfate complexes by X-ray absorption spectroscopy and first principles calculations.

The effect of α-radiolysis on the behavior of heptavalent technetium has been investigated in 13 and 18 M H2SO4. Irradiation experiments were performed using α-particles ((4)He(2+), E = 68 MeV) generated by the ARRONAX cyclotron. UV-visible and X-ray absorption fine structure spectroscopic studies indicate that Tc(VII) is reduced to Tc(V) under α-irradiation.

Reactivity of HTcO(4) with methanol in sulfuric acid: Tc-sulfate complexes revealed by XAFS spectroscopy and first principles calculations.

The reaction between HTcO(4) and MeOH in 13 M H(2)SO(4) was investigated by (99)Tc NMR, UV-visible and X-ray absorption fine structure (XAFS) spectroscopy. Experimental results and first principles calculations show the formation of Tc(+5) sulfate complexes. The results expand the fundamental understanding of Tc in high acid solutions.

[Prevalence and characterization of uropathogenic Escherichia coli producing cytotoxic necrotizing factor type 1 (CNF1) in the center of Tunisia].

During a three-year survey of the prevalence in central Tunisia of Escherichia coli producing CNF1 toxin (NTEC), 716 samples have been investigated by PCR for cnf1 gene. All samples were isolated from urine of adult and children patients presenting significant bacteriuria (> 10(5) colony-forming units/mL), independently of the severity of the clinical presentation; 328 strains were found harboring cnf1 gene, they were distributed into three clinical categories: 219 (66.76%) from patients with symptomatic bacteriuria, 76 (23.