Scleroderma renal crisis: a retrospective multicentre study on 91 patients and 427 controls.

Objective: Scleroderma renal crisis (SRC) is a severe manifestation of SSc, whose prognosis remains severe, despite treatment with angiotensin-converting-enzyme inhibitor and dialysis. This study was undertaken to describe SRC characteristics, prognosis and outcome, and evaluate the responsibility of CSs in its occurrence.

Methods: Analysis concerned 91 SSc patients with SRC who were compared with 427 non-SRC-SSc patients taken as controls.