Publications by authors named "I Dehaene"
Article Synopsis
- Aberrant embryo implantation and placentation can lead to serious pregnancy complications like preeclampsia, and current risk identification methods are not very accurate.
- The ExPECT study aims to validate a cell-free DNA methylation strategy to diagnose preeclampsia early and identify high-risk pregnancies by analyzing blood samples over time.
- Results showed distinct methylation patterns between healthy and affected pregnancies, with significant differences detectable as early as 12 weeks, leading to the development of promising classification models for diagnosis and prediction.
Background: Prematurity remains one of the main causes of neonatal morbidity and mortality. Approximately two thirds of preterm births are spontaneous, i.e.
View Article and Find Full Text PDFBackground: Poor subjective sleep quality, depressive symptoms and fatigue occur frequently in postpartum. However, the dynamics of their respective associations from prepartum throughout the maternity period in function of baby feeding method have not been fully elucidated.
Methods: Prospective, longitudinal study using validated questionnaires probing for sleep quality, insomnia, fatigue and depressive symptoms at 35-37 weeks of gestation and at 2, 8 and 12 weeks postpartum in the obstetric departments of two Flemish hospitals.
Article Synopsis
- Twin pregnancies face a high risk of extreme preterm birth (PTB) under 28 weeks, linked to serious health issues for newborns, and current treatments are limited.
- A potential solution is the placement of a vaginal cerclage for women with a short cervix or cervical dilatation, aiming to reduce the chances of extreme PTB.
- Two multicenter trials are planned in the Netherlands to evaluate the effectiveness of vaginal cerclage compared to standard care in these women, with specific recruitment goals and an analysis of costs and outcomes.