Macroprolactinoma associated with Cushing's disease, successfully treated with cabergoline.

Multiple pituitary hormone hypersecretions have already been described, but the co-occurrence of PRL and ACTH excess is very rare. To our knowledge, medical treatment with cabergoline only, avoiding pituitary surgery and radiotherapy in this type of tumor has never been reported before. This case report deals with a 31-yr-old man affected with a macroprolactinoma associated with a florid clinical image of Cushing's disease.

Renal arterial stenosis as a cause of high output cardiac failure.

A patient is described in whom renal arterial stenosis in a functionally solitary kidney led to arterial hypertension and high output cardiac failure. The pulmonary oedema was resistant to conventional drug therapy but showed prompt regression after percutaneous transluminal angioplasty. This case report demonstrates the usefulness of cardiac output measurement in selected patients presenting with hypertension and pulmonary oedema.