A Case of Duodenal Resection and Duodenojejunostomy for Multiple Small Bowel Infarction in Patient With Inherited Thrombophilia and Vitamin K Antagonist Induced Critical Hypocoagulation.

We present a case of the multiple venous intestinal infarction in patient with two inherited thrombophilias: Leiden factor V (LFV) and factor VIII elevation. The patient had a critical hypocoagulation caused by vitamin K antagonist (VKA) overdose. At laparotomy, several intestinal segments were necrotic and ischemic.

ATTACHMENT OF CHRONIC LYMPHOCYTIC LEUKAEMIA CELLS BY AUTOLOGOUS POLYMORPHONUCLEAR NEUTROPHILS MEDIATED BY BISPECIFIC ANTI-CD19/CD64 ANTIBODY.

Chronic lymphocytic leukemia (CLL) is the most common adult leukaemia in the US and in Europe, including Georgia. CLL presents with clonal expansion and accumulation of CD5+CD19+CD23+ cells in peripheral lymphoid organs and tissues and in bone marrow. The disease remains incurable, albeit there are new molecular and immunotherapy methods currently available, which, in conjunction with chemotherapy, lead to the "precision therapy" approach.

Prognostic significance of apoptosis-related CD95 antigen expression in patients with non-Hodgkin's lymphoma.

Apoptosis-related proteins might play an important role in the pathogenesis and sensibility to the chemotherapeutical drugs in patients with non-Hodgkin's lymphoma (NHL). In our study we tried to find out the relation between the expression of CD95/Fas/Apo-1 antigen and clinical outcome of NHL patients. We have measured 24-hour spontaneous apoptosis of peripheral lymphocytes on flow cytometer using specific monoclonal anti-CD95 mouse antibodies in 54 patients aged 19-76 years.